Cefalotin

• Catalog No.: Bio-0631
• CAS Number: 153-61-7
• M. F.: C16H16N2O6S2
• M. W.: 396.43804

SYNONYMS

• IUPAC name: (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• IUPAC Traditional name: (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Synonyms: Cephalothin; Cephalosporin 871; Cephalotin; 7-(2-Thiopheneacetamido)cephalosporanic acid

DATABASE IDS

• CAS Number: 153-61-7

PROPERTIES

• Application(s): Parenteral antibiotic
• Mechanism of Action: Mucopeptide synthesis inhibitor

REFERENCES

• Chauvette, R.R. et al., J.A.C.S., 1962, 84, 3401, (synth)
• Woodward, R.B. et al., J.A.C.S., 1966, 88, 852, (synth)
• Simmons, R.J., Anal. Profiles Drug Subst., 1972, 1, 319, (rev)
• Welles, J.S., Cephalosporins Penicillins: Chem. Biol., (Flynn, E.H., Ed.), Academic Press, 1972, 583, (rev)
• Ratcliffe, R. et al., Tet. Lett., 1973, 4649
• Nishikawa, J. et al., J. Antibiot., 1982, 35, 1724, (ir, cmr)
• Cowley, B.R. et al., Tetrahedron, 1983, 39, 461, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3941, (synonyms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 138
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CCX250; SFQ500