Luteolin

• Catalog No.: Bio-0604
• CAS Number: 491-70-3
• M. F.: C15H10O6
• M. W.: 286.2363

SYNONYMS

• IUPAC name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
• IUPAC Traditional name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
• Synonyms: Digitoflavone; Flavopurpol; Luteolol; Daphneflavonol

DATABASE IDS

• CAS Number: 491-70-3

PROPERTIES

• Application(s): Antiinflammatory
• Application(s): Antispasmodic
• Application(s): Antitussive agent
• Application(s): Antitumourigenic activity in mice reported
• Application(s): Shows anti-HIV activity
• Biological Source: Occurs in many plants in Leguminosae, Resedaceae, Euphorbiaceae, Umbelliferae, Scrophulariaceae, Fabaceae, Asteraceae, Cistaceae, Passifloraceae, Yerbenaceae and Hepaticae. First isol. in 1832 from Reseda luteola
• Mechanism of Action: Lipid peroxidation inhibitor in rat liver microsomes

REFERENCES

• Perkin, A.G., J.C.S., 1900, 77, 1315, (isol)
• Diller, E., Ber., 1901, 34, 1452, (isol)
• Thieme, H., Tet. Lett., 1968, 2781, (derivs)
• Inouye, H. et al., Chem. Ber., 1969, 102, 3009, (synth)
• Bandyukova, V.A., Khim. Prir. Soedin., 1969, 5, 595
• Dhar, K.L. et al., Planta Med., 1970, 18, 337, (isol, deriv)
• Kingston, D.G.I., Tetrahedron, 1971, 27, 2691, (ms)
• Karrer, W. et al., Konstitution und Vorkommen der Organischen Pflanzenstoffe, 2nd edn., Birkhuser Verlag, Basel, 1972, nos. 1470; 1473, (occur)
• Nevskaya, E.M., Zh. Anal. Khim., 1972, 27, 1699, (use)
• Wagner, H. et al., Tet. Lett., 1976, 1799, (nmr)
• Chari, V.M. et al., Phytochemistry, 1977, 16, 1273, (nmr)
• Voirin, B., Phytochemistry, 1983, 22, 2107, (uv)
• Mansour, R.M.A. et al., Phytochemistry, 1983, 22, 2630, (derivs)
• Tomas, F. et al., Z. Naturforsch., C, 1985, 40, 583
• Plant Flavonoids in Biology and Medicine, (eds. Cody, V. et al), A. R. Liss, N. Y., 1986, (biol, prop)
• Markham, K.R. et al., J. Nat. Prod., 1987, 50, 660, (derivs)
• Cody, V. et al., Plant Flavonoids in Biology and Medicine II, (eds., Cody, V. et al), A.R. Liss, N.Y., 1988, (biol, prop)
• Ono, K., Eur. J. Biochem., 1990, 190, 469, (anti-HIV activity)
• Nagarathnam, D. et al., J.O.C., 1991, 56, 4884, (synth)
• El-Ansari, M.A. et al., Phytochemistry, 1991, 30, 1169, (derivs)
• 1994, 87, 107, (Luteolin, pharmacol)
• Litkei, G. et al., Annalen, 1995, 1711, (synth)
• Youssef, D. et al., Planta Med., 1995, 61, 570, (pmr, cmr)