Benzylpenicillin

• Catalog No.: Bio-0602
• CAS Number: 61-33-6
• M. F.: C16H18N2O4S
• M. W.: 334.39012

SYNONYMS

• IUPAC name: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• IUPAC Traditional name: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• Synonyms: Cilopen; Ursopen; 6-(Phenylacetamido)penicillanic acid; Penicillin G; Novocillin; Phenylacetylpenin; Penicillin II; Benzylpenicillinic acid; Cristapen

DATABASE IDS

• CAS Number: 61-33-6

PROPERTIES

• Application(s): Antibiotic
• Application(s): Shows activity against gram-positive bacteria
• Biological Source: Antibiotic from Penicillium spp. and also other fungal spp.
• Mechanism of Action: Cell-wall mucopeptide synthesis inhibitor
• Mechanism of Action: Binds enicillin-binding-protein-3
• Mechanism of Action: Binds penicillin-binding-protein-1Bs

REFERENCES

• Chain, E.B. et al., Antibiotics, Oxford University Press, 1949, 2, (rev)
• The Chemistry of Penicillin, (eds. Clarke, H.T. et al), Princeton University Press, 1949, (rev)
• Sheehan, J.C. et al., J.A.C.S., 1962, 84, 2983, (synth)
• Bycroft, B.W. et al., Chem. Comm., 1975, 923, (biosynth)
• Bachi, M.D. et al., J.C.S. Perkin 1, 1980, 11, (synth)
• Morin, R.B. et al., Chem. and Biol. of beta-Lactam Antibiotics, (Eds.), Vol. 1, Academic Press, N.Y., 1982, (book)
• Kirschbaum, J., Anal. Profiles Drug Subst., 1986, 15, 427, (rev)
• Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 3, 129, (rev)
• Marchettini, N. et al., Spectrosc. Lett., 1992, 25, 535, (pmr, cmr, conformn)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 121; 122; 148
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 1152
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BDY669; BFD000; PAQ100; BFD250; BFC750