Formononetin

• Catalog No.: Bio-0599
• CAS Number: 485-72-3
• M. F.: C16H12O4
• M. W.: 268.26408

SYNONYMS

• IUPAC name: 7-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
• IUPAC Traditional name: 7-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
• Synonyms: Neochanin; Biochanin B; Formoononetin; Pratol

DATABASE IDS

• CAS Number: 485-72-3

PROPERTIES

• Application(s): Shows estrogenic props.
• Biological Source: Constit. of red and subterranean clovers ( Trifolium pratense and Trifolium subterraneum ) and of Chana ( Cicer arietinum ). Constit. of the heartwood of Pterocarpus indicus. Found also in Baptisia australis . Widely distributed in the Leguminosae (Papilionoideae). Also in Virola caducifolia and Virola multinervia (Myricaceae)
• Mechanism of Action: Estrogen

REFERENCES

• Bose, J.L., J. Sci. Ind. Res., Sect. B, 1951, 10, 291, (isol, struct)
• Bradbury, R.B., J.C.S., 1951, 3447, (isol)
• Baker, W. et al., J.C.S., 1953, 1852, (synth)
• Cooke, R.G., Aust. J. Chem., 1964, 17, 379, (isol, struct)
• Lebreton, P. et al., Phytochemistry, 1967, 6, 1675, (isol)
• Benn, M.H., Can. J. Chem., 1970, 48, 1624, (isol)
• Braz Filho, R. et al., J. Nat. Prod., 1977, 40, 236, (isol)
• Jha, H.C. et al., Angew. Chem., Int. Ed., 1981, 20, 102, (synth)
• Ingham, J.L., Prog. Chem. Org. Nat. Prod., 1983, 43, 1, (rev, occur)
• Al-Ani, H.A.M. et al., J.C.S. Perkin 1, 1984, 2831, (biosynth)
• Elgamal, M.H.A. et al., J. Prakt. Chem., 1986, 328, 893, (ms)
• Murthy, M.S.R. et al., Magn. Reson. Chem., 1986, 24, 225, (cmr)
• Wu, L.J. et al., Yakugaku Zasshi, 1986, 106, 22, (Kushenol O)
• Pivovarenko, V.G. et al., Khim. Prir. Soedin., 1989, 25, 639; Chem. Nat. Compd. (Engl. Transl.), 1989, 25, 542, (synth)