Nalidixic acid

• Catalog No.: Bio-0593
• CAS Number: 389-08-2
• M. F.: C12H12N2O3
• M. W.: 232.23528

SYNONYMS

• IUPAC name: 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• IUPAC Traditional name: 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• Synonyms: Nalidixanum; Nalidixin; Wintomylon; Cybis; Negram

DATABASE IDS

• CAS Number: 389-08-2

PROPERTIES

• Application(s): Antibacterial agent
• Application(s): Antibiotic
• Application(s): Antiseptic
• Mechanism of Action: DNA polymerase inhibitor

REFERENCES

• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, EID000
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 473B, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 889B, (ir)
• Lesher, G.Y. et al., J. Med. Chem., 1962, 5, 1063
• Santielli, A.A. et al., J. Med. Chem., 1975, 18, 1038, (synth)
• Lesher, G.Y., Kirk-Othmer Encycl. Chem. Technol., 3rd edn., Wiley, 1978, 2, 782, (rev)
• Grubb, P.E., Anal. Profiles Drug Subst., 1979, 8, 371, (rev)
• Huber, C.P. et al., Acta Cryst. B, 1980, 36, 497, (cryst struct)
• Koch, H. et al., Pharm. Int., 1980, 1, 108, (rev, pharmacol)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 2267
• Morrissey, R.E. et al., Drug Chem. Toxicol., 1991, 14, 45, (tox)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 184