Acaciin

• Catalog No.: Bio-0591
• CAS Number: 480-36-4
• M. F.: C28H32O14
• M. W.: 592.54528

SYNONYMS

• IUPAC name: 5-hydroxy-2-(4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one
• IUPAC Traditional name: 5-hydroxy-2-(4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one
• Synonyms: Linarin; Linaric acid; Buddleoflavonoloside; Acaciin; Acacetin 7-rutinoside

DATABASE IDS

• CAS Number: 480-36-4

PROPERTIES

• Application(s): Antidiabetic
• Biological Source: Occurs in Linaria vulgaris, Robinia and Micromeria spp. and other plants
• Mechanism of Action: Aldose reductase inhibitor

REFERENCES

• Robinson, R. et al., J.C.S., 1926, 128, 2344, (synth)
• Freudenberg, K. et al., Annalen, 1954, 587, 207, (Acacetin trioside)
• Shibata, S. et al., Yakugaku Zasshi, 1960, 80, 620; CA, 54, 21488, (pharmacol)
• Nakaoki, T. et al., CA, 1961, 55, 10803, (deriv)
• Massicot, J. et al., Bull. Soc. Chim. Fr., 1963, 2712, (pmr)
• Nogradi, M. et al., Chem. Ber., 1967, 100, 2783, (deriv)
• Wagner, H. et al., Chem. Ber., 1969, 102, 1445; 2083; 1970, 103, 851, (derivs)
• Khadzhai, Y. et al., Farmakol. Toksikol. (Moscow), 1969, 32, 451, (pharmacol)
• Bowie, J.H. et al., J.C.S.(B), 1969, 2, 89, (ms)
• Okigawa, M. et al., Tet. Lett., 1970, 2935, (deriv)
• Nevskaya, E.M. et al., Zh. Anal. Khim., 1972, 27, 1699, (use)
• Wagner, H. et al., Tet. Lett., 1976, 1799, (nmr)
• Gaydou, E.M. et al., Bull. Soc. Chim. Fr., 1978, 43, (synth, pmr, uv)