Esculetin

• Catalog No.: Bio-0588
• CAS Number: 305-01-1
• M. F.: C9H6O4
• M. W.: 178.14154

SYNONYMS

• IUPAC name: 6,7-dihydroxy-2H-chromen-2-one
• IUPAC Traditional name: 6,7-dihydroxy-2H-chromen-2-one
• Synonyms: Esculetol; esculetin; cichorigenin; 6,7-dihydroxycoumarin; Aesculetin

DATABASE IDS

• CAS Number: 305-01-1

PROPERTIES

• Application(s): Antifungal
• Biological Source: Metab. of infected sweet potato also found in Aesculus, Atropa, Datura, Digitalis and other plants; found in some ferns
• Mechanism of Action: Leukotriene antagonist in-vitro
• Mechanism of Action: Prostaglandin antagonist

REFERENCES

• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 324A; 324C; 326C, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1314C; 1318A, (nmr)
• Head, F.S.H. et al., J.C.S., 1939, 1266, (synth)
• Bohlmann, F. et al., Chem. Ber., 1957, 90, 1512, (synth)
• Jain, B.D., Anal. Chim. Acta, 1967, 37, 1358, (detn, Nb, U)
• Bursey, M.M. et al., Chem. Comm., 1967, 712, (ms)
• Karrer, W. et al., Konstitution und Vorkommen der Organischen Pflanzenstoffe, 2nd edn., Birkhuser Verlag, Basel, 1972, nos. 1325-1327, (occur)
• Sato, M. et al., Phytochemistry, 1972, 11, 657, (biosynth)
• Gnther, H. et al., Org. Magn. Reson., 1975, 7, 339, (cmr, deriv)
• Cussans, N.J. et al., Tetrahedron, 1975, 31, 2719, (cmr)
• Ashwood-Smith, M.J. et al., Experientia, 1982, 39, 262, (physiol, tox, deriv)
• Murray, R.D.H. et al., The Natural Coumarins, J. Wiley, 1982, (occur, rev)
• Kelkar, S.L. et al., Indian J. Chem., Sect. B, 1984, 23, 458, (synth)
• Joseph-Nathan, P. et al., J. Het. Chem., 1984, 21, 1141, (pmr, deriv)
• Abu-Eittah, R.H. et al., Can. J. Chem., 1985, 63, 1173, (uv)
• Jackson, Y.A. et al., Heterocycles, 1995, 41, 1979, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DRS800