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Warfarin

Catalog No. Bio-0586 Name InterBioScreen
CAS Number 81-81-2 Website http://www.ibscreen.com
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Storage Chembase ID: 108455

SYNONYMS

IUPAC name
4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
IUPAC Traditional name
4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
Synonyms
Kumatox
Coumadin
Panwarfin
Ratron
Vampirinip
Coumafene
Aldocumar
Marevan
Waran
Zoocoumarin

DATABASE IDS

CAS Number 81-81-2

PROPERTIES

Application(s) Anticoagulant
Application(s) Orally active anticoagulant which depresses synthesis of vitamin K-dependent coagulation factors.
Application(s) Used in treatment and prophylaxis of thromboembolic disorders
Description Rotamers
Mechanism of Action Prothrombin depletor
Mechanism of Action Clotting factor sythesis inhibitor
Mechanism of Action Interferes withsynthesis of menadione-dependent clotting factors
Mechanism of Action Depletes clotting factor-VII
Mechanism of Action Depletes clotting factor-IX
Mechanism of Action Depletes clotting factor-X

DETAILS

REFERENCES

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  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1319C, (nmr)
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  • Valente, E.J. et al., Acta Cryst. B, 1975, 31, 954, (abs config)
  • Valente, E.J. et al., J. Med. Chem., 1977, 21, 141; 231, (uv, pmr)
  • Chan, K.K. et al., Tetrahedron, 1977, 33, 899, (cmr)
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