Adenosine

• Catalog No.: Bio-0580
• CAS Number: 58-61-7
• M. F.: C10H13N5O4
• M. W.: 267.24132

SYNONYMS

• IUPAC name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• IUPAC Traditional name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• Synonyms: Adenocard; Adenocor; Adenoscan

DATABASE IDS

• CAS Number: 58-61-7

PROPERTIES

• Application(s): Antiarrhythmic agent
• Application(s): Cardiac depressant
• Application(s): Purinergic
• Biological Source: Widely distributed in nature. One of the four principal nucleosides of nucleic acid
• Mechanism of Action: Adenosine-a1-agonist
• Mechanism of Action: Adenosine-a2-agonist

REFERENCES

• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 719C; 720A; 721A; 722C; 725B, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 222A; 224A; 227B; 229B, (nmr)
• Davoll, J. et al., J.C.S., 1948, 967-969, (synth)
• Brown, D.M. et al., J.C.S., 1950, 3299-3304, (synth)
• Biemann, K. et al., J.A.C.S., 1962, 84, 2005-2007, (ms)
• Shikata, K. et al., Acta Cryst. B, 1973, 29, 31-38, (cryst struct)
• Sarma, R.H. et al., J.A.C.S., 1974, 96, 7337-7348, (pmr, conformn)
• Earl, R.A. et al., J.O.C., 1975, 40, 1822-1828, (cmr)
• Wilson, C.C. et al., Acta Cryst. C, 1986, 42, 697-700, (cryst struct, triacetyl)
• Puech, P. et al., Handb. Exp. Pharmacol., 1989, 89, 453-460, (rev, metab, props, use)
• Adenosine and Adenosine Receptors, Williams, M., ed., Chapman and Hall, 1990, (book)
• Pinski, S.L. et al., Cleveland Clin. J. Med., 1990, 57, 383, (use)
• Reddy, A.M. et al., J. Het. Chem., 1990, 27, 1297-1305, (ms)
• Morgan, J.M. et al., Circulation, 1991, 84, 1145, (use)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 57
• Mahler, G.S., Anal. Profiles Drug Subst., 1998, 25, 1-37, (rev)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AEH750