Norharman

• Catalog No.: Bio-0577
• CAS Number: 244-63-3
• M. F.: C11H8N2
• M. W.: 168.19462

SYNONYMS

• IUPAC name: 9H-pyrido[3,4-b]indole
• IUPAC Traditional name: 9H-pyrido[3,4-b]indole
• Synonyms: Carbazoline; 2,9-Diazafluorene; 2-Carboline

DATABASE IDS

• CAS Number: 244-63-3

PROPERTIES

• Biological Source: Alkaloid from Chrysophyllum lacourtianum, Nocardia sp. and Streptomyces sp., also present in tobacco smoke, Catharanthus roseus leaves, Lolium perenne and Festuca arundinacea (Sapotaceae, Apocynaceae, Gramineae). A metab. from the New Zealand ascidian Ritterella sigillinoides
• Application(s): Plant growth and enzyme inhibitor
• Mechanism of Action: Sympatholytic-alpha

REFERENCES

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• Henecka, H. et al., CA, 1964, 60, 5471
• Coutts, R.T. et al., Org. Mass Spectrom., 1970, 3, 879, (ms)
• Balkau, F. et al., Aust. J. Chem., 1973, 26, 1501, (pmr)
• Bush, L.P. et al., J. Chromatogr., 1975, 111, 165, (isol)
• Deumie, M. et al., J. Photochem., 1979, 10, 365, (uv)
• Bobbitt, J.M. et al., J.O.C., 1980, 45, 1978, (synth)
• Sugimura, T. et al., Biol. React. Intermed. 2, Chem. Mech. Biol. Eff., Snyder, R. et al (ed.), (see Adv. Exp. Med. Biol. v136A-136B), Plenum Press, 1982, 1011, (comutagenicity)
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• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, NNR300
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 681D, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 164C, (nmr)
• Perkin, W.H. et al., J.C.S., 1921, 119, 1602
• Gulland, J.M. et al., J.C.S., 1929, 2926
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