Cefazolin

• Catalog No.: Bio-0576
• CAS Number: 25953-19-9
• M. F.: C14H14N8O4S3
• M. W.: 454.50716

SYNONYMS

• IUPAC name: (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• IUPAC Traditional name: (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Synonyms: Cephamezine

DATABASE IDS

• CAS Number: 25953-19-9

PROPERTIES

• Application(s): Antibiotic
• Mechanism of Action: Mucopeptide synthesis inhibitor

REFERENCES

• Shibata, H. et al., Antimicrob. Agents Chemother., 1970, 467, (props)
• Kariyone, K. et al., J. Antibiot., 1970, 23, 131, (synth, props)
• Zappala, A.E., Anal. Profiles Drug Subst., 1975, 4, 1, (rev)
• Nakano, H., Pharmacol. Biochem. Prop. Drug Subst., 1977, 1, 155, (rev)
• Van Meerssche, M. et al., Cryst. Struct. Commun., 1979, 8, 281, (cryst struct)
• Muneyuki, R. et al., Chem. Ind. (London), 1981, 159, (synth)
• Tori, K. et al., Tet. Lett., 1981, 22, 2793, (cmr)
• Palomo-Coll, A. et al., Tetrahedron, 1985, 41, 5133, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3103, (synonyms)
• Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 3, 28, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 140
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CCS250