Orbifloxacin

• Catalog No.: Bio-0533
• CAS Number: 113617-63-3
• M. F.: C19H20F3N3O3
• M. W.: 395.3756096

SYNONYMS

• IUPAC name: 1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• IUPAC Traditional name: 1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• Synonyms: Orbax

DATABASE IDS

• CAS Number: 113617-63-3

PROPERTIES

• Application(s): Antibacterial agent
• Application(s): Antiseptic
• Application(s): Antibiotic
• Mechanism of Action: Inhibitor of bacterial DNA gyrase,
• Mechanism of Action: Prevents DNA supercoiling and synthesis

REFERENCES

• Eur. Pat., 1987, Dainippon, 242 789; CA, 108, 150325x, (synth, pharmacol)
• Miyamoto, T. et al., J. Med. Chem., 1990, 33, 1645-1656, (synth, pmr, ir, pharmacol)
• Morimura, T. et al., Chem. Pharm. Bull., 1995, 43, 1000-1004; 1997, 45, 373-377, (photodegradation)
• Nakamura, S. et al., Drugs, 1995, 49, 152-158, (rev)