Oxcarbazepine

• Catalog No.: Bio-0527
• CAS Number: 28721-07-5
• M. F.: C15H12N2O2
• M. W.: 252.26798

SYNONYMS

• IUPAC name: 9-oxo-2-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide
• IUPAC Traditional name: 9-oxo-2-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaene-2-carboxamide
• Synonyms: Trileptal; Oxcarb

DATABASE IDS

• CAS Number: 28721-07-5

PROPERTIES

• Application(s): Neuroleptic agent
• Application(s): Anticonvulsant
• Application(s): Analgesic
• Mechanism of Action: Gabaminergic-A
• Mechanism of Action: Sympathomimetic-Alpha-2
• Mechanism of Action: Adenosine-Agonist-A1
• Mechanism of Action: Sodium channel inhibitor

REFERENCES

• U.K. Pat., 1963, 943 277; CA, 61, 1815f, (synth)
• Ger. Pat., 1970, 2 011 087; CA, 73, 109711r, (deriv, synth, pharmacol)
• Feldmann, K.F. et al., Adv. Epileptol., 1981, 12, 89, (metab)
• Theisohn, M. et al., Eur. J. Clin. Pharmacol., 1982, 22, 545, (metab)
• Kumps, A., J. Liq. Chromatogr., 1984, 7, 1235, (hplc)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 301
• Schachter, S.C. et al., Expert Opin. Invest. Drugs, 1999, 8, 1103-1112
• Lohse, O. et al., Tet. Lett., 2001, 42, 385-389, (deriv, synth)