Aceclofenac

• Catalog No.: Bio-0525
• CAS Number: 89796-99-6
• M. F.: C16H13Cl2NO4
• M. W.: 354.18472

SYNONYMS

• IUPAC name: 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid
• IUPAC Traditional name: 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid
• Synonyms: Airtal; Gerbin; Tresquim

DATABASE IDS

• CAS Number: 89796-99-6

PROPERTIES

• Application(s): Analgesic
• Application(s): Antiinflammatory agent
• Mechanism of Action: Prostaglandin-Antagonist-E2
• Mechanism of Action: Cyclooxygenase-Inhibitor-1
• Mechanism of Action: Cyclooxygenase-Inhibitor-2

REFERENCES

• Ger. Pat., 1969, 1 815 802; CA, 72, 12385d, (synth)
• Menasse-Gdynia, R. et al., Experientia, 1973, 29, 450, (pharmacol)
• Kracmar, J. et al., Pharmazie, 1976, 31, 614, (uv)
• Tamura, Y. et al., Chem. Pharm. Bull., 1984, 32, 1995, (synth)
• Spanish Pat., 1984, 520 813; CA, 104, 88301, (Aceclofenac)
• Sallman, A.R. et al., Am. J. Med., 1986, 80, 1, (revs)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3010, (synonyms)
• Todd, P.A. et al., Drugs, 1988, 35, 244, (rev)
• Adeyeye, C.M. et al., Anal. Profiles Drug Subst., 1990, 19, 123, (rev)
• Grau, M. et al., Arzneim.-Forsch., 1991, 41, 1265, (Aceclofenac, rev)
• Castellari, C. et al., Acta Cryst. C, 1994, 50, 1723; 1997, 53, 794-797, (cryst struct)
• Hanses, A. et al., Arch. Pharm. (Weinheim, Ger.), 1995, 328, 257, (hplc)
• Brogden, R.N. et al., Drugs, 1996, 52, 113, (Aceclofenac, rev, pharmacol)
• McNeely, W. et al., Drugs, 1999, 57, 991-1003, (rev)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 12; 31
• Dooley, M. et al., Drugs, 2001, 61, 1351-1378, (rev)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DEO600