Secnidazole

• Catalog No.: Bio-0524
• CAS Number: 3366-95-8
• M. F.: C7H11N3O3
• M. W.: 185.18054

SYNONYMS

• IUPAC name: 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
• IUPAC Traditional name: 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
• Synonyms: Flagentyl; Secnidal; Flow; Apex; Daksol; Famide

DATABASE IDS

• CAS Number: 3366-95-8

PROPERTIES

• Application(s): Antimicrobial agent
• Application(s): Amoebicide
• Application(s): Trichomonacide
• Application(s): Protozoacide
• Mechanism of Action: Interacts with DNA to cause a loss of helical DNA structure and strand breakage resulting in inhibition of protein synthesis and cell death in susceptible organisms

REFERENCES

• Cosar, C. et al., Arzneim.-Forsch., 1966, 16, 23, (synth, pharmacol)
• Nagarajan, K. et al., Indian J. Chem., Sect. B, 1982, 21, 1006, (uv, pmr, ms)
• Bhatia, S.C. et al., J. Chromatogr., 1984, 305, 325, (gc)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 526
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 875, (synonyms)