Sulfamerazine

• Catalog No.: Bio-0519
• CAS Number: 127-79-7
• M. F.: C11H12N4O2S
• M. W.: 264.30358

SYNONYMS

• IUPAC name: 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide
• IUPAC Traditional name: 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide
• Synonyms: 4-Methylsulfadiazine; 2-Sulfanilamido-4-methylpyrimidine; Sulfamethyldiazine

DATABASE IDS

• CAS Number: 127-79-7

PROPERTIES

• Application(s): Antiseptic
• Mechanism of Action: Folic acid biosynthesis antagonist

REFERENCES

• Roblin, R.O. et al., J.A.C.S., 1940, 62, 2002, (synth)
• Sprague, J.M. et al., J.A.C.S., 1941, 63, 3028, (synth)
• Moriguchi, I. et al., Chem. Pharm. Bull., 1969, 17, 2554, (pharmacol)
• Pogorzhel'skaya, N.A. et al., Zh. Org. Khim., 1969, 5, 1179, (synth)
• Chang, C.J. et al., J. Med. Chem., 1975, 18, 505, (nmr)
• Przybylski, M. et al., Adv. Mass Spectrom. Biochem. Med., Proc. Int. Symp. Mass Spectrom. Biochem. Med. 2nd, 3rd, 1976, 1, 309, (ms)
• Woolfenden, R.D.G., Anal. Profiles Drug Subst., 1977, 6, 515, (rev, synth, props, anal)
• Acharya, K.R. et al., J. Crystallogr. Spectrosc. Res., 1982, 12, 369, (cryst struct)
• Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr, tautom)
• Maury, L. et al., Farmaco, Ed. Prat., 1986, 41, 26, (ir, uv, Raman)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1930
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 205
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, ALF250; SJW475