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Gliclazide

Catalog No. Bio-0502 Name InterBioScreen
CAS Number 21187-98-4 Website http://www.ibscreen.com
M. F. C15H21N3O3S Telephone +7 49652 40091
M. W. 323.41054 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 991

SYNONYMS

IUPAC name
1-(4-methylbenzenesulfonyl)-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea
IUPAC Traditional name
1-(4-methylbenzenesulfonyl)-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea
Synonyms
Diabrezide
Glimicron
Nordialex
Diamicron
Glyclazide
Unava

DATABASE IDS

CAS Number 21187-98-4

PROPERTIES

Application(s) Antidiabetic
Application(s) Oral antihyperglycaemic agent
Mechanism of Action Appears to enhance glucose stimulated insulin secretion at a submaximally stimulating blood-glucose level

DETAILS

REFERENCES

  • U.K. Pat., 1968, 1 153 982; CA, 70, 47290e, (synth)
  • Duhault, J. et al., Arzneim.-Forsch., 1972, 22, 1682, (pharmacol, tox)
  • Keen, H. et al., Int. Congr. Symp. Ser. R. Soc. Med., No. 20, 1980
  • Holmes, B. et al., Drugs, 1984, 27, 301, (rev)
  • Oida, T. et al., Xenobiotica, 1985, 15, 87, (metab)
  • Palmer, K.J. et al., Drugs, 1993, 46, 92, (rev)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 279
  • Winters, C.S. et al., J. Pharm. Sci., 1994, 83, 300, (cmr, cryst struct)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 4770, (synonyms)
  • Parvez, M. et al., Acta Cryst. C, 1999, 55, 74-75, (cryst struct)
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DBL700