Benzoclidine

• Catalog No.: Bio-0483
• CAS Number: 16852-81-6
• M. F.: C14H17NO2
• M. W.: 231.29028

SYNONYMS

• IUPAC name: 1-azabicyclo[2.2.2]octan-3-yl benzoate
• IUPAC Traditional name: 1-azabicyclo[2.2.2]octan-3-yl benzoate
• Synonyms: Oxylidine; 3-Benzoyloxyquinoline; Oxilidin

DATABASE IDS

• CAS Number: 16852-81-6

PROPERTIES

• Application(s): Antihypertensive
• Application(s): Sedative
• Mechanism of Action: Parasympathomimetic

REFERENCES

• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 1, 379D, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 1, 592B, (nmr)
• Sternbach, L.H. et al., J.A.C.S., 1952, 74, 2215, (synth)
• Grob, C.A. et al., Helv. Chim. Acta, 1957, 40, 2170, (synth, derivs)
• Aaron, H.S. et al., J.O.C., 1965, 30, 1331, (synth)
• Nogrady, T. et al., J. Med. Chem., 1968, 11, 212, (pharmacol, deriv)
• Albanus, L., Acta Pharmacol. Toxicol., 1970, 28, 305, (deriv, pharmacol)
• Kostyanovsky, R.G. et al., Org. Mass Spectrom., 1970, 3, 1023, (ms)
• Baker, R.W. et al., J.C.S. Perkin 2, 1972, 2340, (cryst struct, abs config)
• Lambrecht, G., Arch. Pharm. (Weinheim, Ger.), 1976, 309, 235, (resoln)
• Lambrecht, G., Eur. J. Med. Chem. (Chim. Ther.), 1976, 11, 46, (deriv, pharmacol)
• Fieser and Fieser's Reagents for Organic Synthesis, Wiley, 1977, 6, 501
• Becker, K.B. et al., Helv. Chim. Acta, 1978, 61, 2596, (cmr)
• Ringdahl, B. et al., CA, 1980, 92, 41726j, (resoln)
• Ringdahl, B. et al., Mol. Pharmacol., 1982, 21, 594, (aceclidine, pharmacol)
• Langlois, M. et al., Synth. Commun., 1992, 22, 1895, (resoln, acetate)
• Encyclopaedia of Reagents for Organic Synthesis, (ed. Paquette, L.A.), Wiley, 1995, 6, 4399-4400, (use)
• Ehlert, F.J. et al., J. Pharmacol. Exp. Ther., 1996, 279, 1335, (aceclidine, enantiomers, pharmacol)
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 1416, (aceclidine)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AAE250; QVA000; QWJ000