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Aconiazide

Catalog No. Bio-0482 Name InterBioScreen
CAS Number 13410-86-1 Website http://www.ibscreen.com
M. F. C15H13N3O4 Telephone +7 49652 40091
M. W. 299.28142 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 179820

SYNONYMS

IUPAC name
2-{2-[(1E)-[(pyridin-4-ylformamido)imino]methyl]phenoxy}acetic acid
IUPAC Traditional name
2-{2-[(1E)-[(pyridin-4-ylformamido)imino]methyl]phenoxy}acetic acid
Synonyms
Isonicophen
Phenoxalid

DATABASE IDS

CAS Number 13410-86-1

PROPERTIES

Application(s) Tuberculostatic
Application(s) Antibacterial agent
Application(s) Antiseptic
Description Isomers(~5:1)
Mechanism of Action Interferes with several bacterial Enzyme systems
Mechanism of Action Inhibitor of mycolic acid synthesis and disruption of the cell wall in susceptible organisms

DETAILS

REFERENCES

  • Oeriu, S. et al., Rev. Chim., Acad. Repub. Pop. Roum., 1957, 2, 81; CA, 52, 14870, (synth, pharmacol)
  • Dooley, K.L. et al., J. Am. Coll. Toxicol., 1993, 12, 329, (tox)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 113
  • Peloquin, C.A. et al., Pharmacotherapy (Carlisle, Mass.), 1994, 14, 415, (pharmacokinet, human)