Salinazid

• Catalog No.: Bio-0425
• CAS Number: 495-84-1
• M. F.: C13H11N3O2
• M. W.: 241.24534

SYNONYMS

• IUPAC name: N'-[(1E)-(2-hydroxyphenyl)methylidene]pyridine-4-carbohydrazide
• IUPAC Traditional name: N'-[(1E)-(2-hydroxyphenyl)methylidene]pyridine-4-carbohydrazide
• Synonyms: Salizid; Phthiosan; Nilazid; Nicozid; Salicylaldehyde isonicotinoylhydrazone; Acozid; Nupasal; Saliniazid

DATABASE IDS

• CAS Number: 495-84-1

PROPERTIES

• Application(s): Antiseptic
• Application(s): Used in treatment of tuberculosis
• Mechanism of Action: Interferes with several bacterial Enzyme systems
• Mechanism of Action: Inhibitor of mycolic acid synthesis and disruption of the cell wall in susceptible organisms

REFERENCES

• Yale, H. et al., J.A.C.S., 1953, 75, 1933, (synth)
• Hart, J.J.D. et al., Antibiot. Chemother. (Washington, D.C.), 1954, 4, 803, (synth, props)
• Bavin, E.M. et al., J. Pharm. Pharmacol., 1955, 7, 1032, (pharmacol, tox)
• Chakvaranty, D. et al., J. Pharm. Sci., 1964, 53, 1036, (synth, use)
• Cowper, A.J. et al., J. Inst. Chem. (India), 1981, 53, 111; 195, (synth, pharmacol)
• Martindale, The Extra Pharmacopoeia, 28th/29th edn., Pharmaceutical Press, 1982, 7570