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Sulfalene

Catalog No. Bio-0403 Name InterBioScreen
CAS Number 152-47-6 Website http://www.ibscreen.com
M. F. C11H12N4O3S Telephone +7 49652 40091
M. W. 280.30298 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 546

SYNONYMS

IUPAC name
4-amino-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide
IUPAC Traditional name
4-amino-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide
Synonyms
Kelfizine
Sulfamethoxypyrazine
Dalysep
Longum
Polycidal

DATABASE IDS

CAS Number 152-47-6

PROPERTIES

Application(s) Antiseptic
Application(s) Long-acting sulfonamide used in treatment of respiratory and urinary-tract infections
Mechanism of Action Competitive inhibitor of bacterial para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase
Mechanism of Action The inhibited reaction is necessary in these organisms for the synthesis of folic acid

DETAILS

REFERENCES

  • Launchbury, A.P., Pharm. J., 1975, 214, 14, (pharmacol)
  • Kracmar, J. et al., Pharmazie, 1975, 30, 447, (uv)
  • Padeiskaya, E.N. et al., Khim.-Farm. Zh., 1977, 11, 141, (rev, pharmacol)
  • Botta, M. et al., J. Het. Chem., 1979, 16, 193, (synth)
  • Anisimova, O.S. et al., Khim.-Farm. Zh., 1980, 14, 92, (ms)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 205
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MFN500