Mafenide

• Catalog No.: Bio-0388
• CAS Number: 138-39-6
• M. F.: C7H10N2O2S
• M. W.: 186.2315

SYNONYMS

• IUPAC name: 4-(aminomethyl)benzene-1-sulfonamide
• IUPAC Traditional name: 4-(aminomethyl)benzene-1-sulfonamide
• Synonyms: 4-Homosulfanilamide; Sulfabenzamine; Sulfamylon; Homosul

DATABASE IDS

• CAS Number: 138-39-6

PROPERTIES

• Application(s): Used as an antibacterial agent in treatment of second- and third-degree burns
• Application(s): Antiseptic
• Mechanism of Action: Folic acid biosynthesis antagonist

REFERENCES

• Miller, E. et al., J.A.C.S., 1940, 62, 2099, (synth)
• Bergeim, F.H. et al., J.A.C.S., 1944, 66, 1459, (synth)
• Japan. Pat., 1949, 177 844; CA, 45, 9404, (manuf)
• Momose, T. et al., Yakugaku Zasshi, 1950, 70, 14, (cryst struct)
• Chang, Y.-T. et al., CA, 1953, 47, 7103, (tox)
• Maschka, A. et al., Monatsh. Chem., 1954, 85, 168, (uv)
• Tanaka, Y. et al., Chem. Pharm. Bull., 1965, 13, 399, (ir)
• Meyer-Dulheuer, K.H. et al., Pharm. Ztg., 1965, 110
• Rakoczy, R. et al., J. Med. Chem., 1967, 10, 273, (salts)
• Chatterjee, C. et al., Acta Cryst. B, 1981, 3, 1835, (cryst struct)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 727, (synonyms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 179
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MAC000