Naphthylin

• Catalog No.: Bio-0371
• CAS Number: 1786-03-4
• M. F.: C19H12O2
• M. W.: 272.29738

SYNONYMS

• IUPAC name: 2-(naphthalen-1-yl)-2,3-dihydro-1H-indene-1,3-dione
• IUPAC Traditional name: 2-(naphthalen-1-yl)-2,3-dihydro-1H-indene-1,3-dione
• Synonyms: 2-(1-Naphthyl)-1,3-indanedione

DATABASE IDS

• CAS Number: 1786-03-4

PROPERTIES

• Application(s): Anticoagulant
• Description: Keto/enol 1:3
• Mechanism of Action: Antioxydant
• Mechanism of Action: Interferes with synthesis of vitamin-K-dependent Clotting-factors
• Mechanism of Action: Depletes clotting-factor-VII
• Mechanism of Action: Depletes clotting-factor-IX
• Mechanism of Action: Depletes clotting-factor-X
• Mechanism of Action: Depletes prothrombin

REFERENCES

• Eckstein, M. et al., CA, 1959, 53, 6175, (synth)
• Shapiro, S.L. et al., J.O.C., 1960, 25, 1860; 1961, 26, 3580, (synth, props)
• Perjessy, A. et al., Tetrahedron, 1971, 27, 6159, (ir)
• Fanelli, O., Arzneim.-Forsch., 1975, 25, 873, (pharmacol)
• Csoregh, I. et al., Acta Cryst. B, 1979, 35, 852, (cryst struct)
• Murthy, A.R. et al., J. Med. Chem., 1985, 28, 1591, (synth, props)