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Methylphenobarbital

Catalog No. Bio-0356 Name InterBioScreen
CAS Number 115-38-8 Website http://www.ibscreen.com
M. F. C13H14N2O3 Telephone +7 49652 40091
M. W. 246.26186 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 727

SYNONYMS

IUPAC name
5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
IUPAC Traditional name
5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
Synonyms
Mentabal
Mephobarbital
Methylphenobarbitone
Mebaral
Prominal
Enfenemal
Enphenemal
Mefobarbital
Phemitone

DATABASE IDS

CAS Number 115-38-8

PROPERTIES

Application(s) Antispasmodic
Application(s) Anticonvulsant
Application(s) Analgesic
Application(s) Sedative
Mechanism of Action Dose-dependent respiratory depressant
Mechanism of Action Binds brain tissue protein
Mechanism of Action Produces all levels of CNS mood alteration
Mechanism of Action Binds plasma-protein

DETAILS

REFERENCES

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  • Advovich, H.W. et al., Can. J. Pharm. Sci., 1969, 4, 51, (pmr)
  • Craig, C.R. et al., J. Pharmacol. Exp. Ther., 1971, 176, 35, (pharmacol)
  • Knabe, J. et al., Arch. Pharm. (Weinheim, Ger.), 1972, 305, 54, (synth)
  • Saferstein, R. et al., J. Assoc. Off. Anal. Chem., 1973, 56, 1234, (ms)
  • Dilli, S. et al., Aust. J. Chem., 1975, 28, 2265, (synth)
  • Siek, T.J. et al., J. Forensic Sci., 1975, 20, 18, (uv)
  • Asada, S. et al., Bull. Chem. Soc. Jpn., 1978, 51, 3379, (cmr)
  • Hooper, W.D. et al., Ther. Drug Monit., 1981, 3, 39, (metab)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 2742, (synonyms)
  • Murata, M. et al., Chem. Pharm. Bull., 1992, 40, 2605, (synth, R-form)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 301
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, ENB500