Methylphenobarbital

• Catalog No.: Bio-0356
• CAS Number: 115-38-8
• M. F.: C13H14N2O3
• M. W.: 246.26186

SYNONYMS

• IUPAC name: 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
• IUPAC Traditional name: 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
• Synonyms: Mentabal; Mephobarbital; Methylphenobarbitone; Mebaral; Prominal; Enfenemal; Enphenemal; Mefobarbital; Phemitone

DATABASE IDS

• CAS Number: 115-38-8

PROPERTIES

• Application(s): Antispasmodic
• Application(s): Anticonvulsant
• Application(s): Analgesic
• Application(s): Sedative
• Mechanism of Action: Dose-dependent respiratory depressant
• Mechanism of Action: Binds brain tissue protein
• Mechanism of Action: Produces all levels of CNS mood alteration
• Mechanism of Action: Binds plasma-protein

REFERENCES

• U.K. Pat., 1929, 339 937; CA, 25, 2738, (synth)
• Advovich, H.W. et al., Can. J. Pharm. Sci., 1969, 4, 51, (pmr)
• Craig, C.R. et al., J. Pharmacol. Exp. Ther., 1971, 176, 35, (pharmacol)
• Knabe, J. et al., Arch. Pharm. (Weinheim, Ger.), 1972, 305, 54, (synth)
• Saferstein, R. et al., J. Assoc. Off. Anal. Chem., 1973, 56, 1234, (ms)
• Dilli, S. et al., Aust. J. Chem., 1975, 28, 2265, (synth)
• Siek, T.J. et al., J. Forensic Sci., 1975, 20, 18, (uv)
• Asada, S. et al., Bull. Chem. Soc. Jpn., 1978, 51, 3379, (cmr)
• Hooper, W.D. et al., Ther. Drug Monit., 1981, 3, 39, (metab)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 2742, (synonyms)
• Murata, M. et al., Chem. Pharm. Bull., 1992, 40, 2605, (synth, R-form)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 301
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, ENB500