Phenolphthalein

• Catalog No.: Bio-0349
• CAS Number: 77-09-8
• M. F.: C20H14O4
• M. W.: 318.32276

SYNONYMS

• IUPAC name: 3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one
• IUPAC Traditional name: 3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one
• Synonyms: Dihydroxyphthalophenone; Trihydroxytriphenylmethane-2-carboxylic acid lactone

DATABASE IDS

• CAS Number: 77-09-8

PROPERTIES

• Application(s): Laxatives
• Mechanism of Action: Alters electrolyte-secretion
• Mechanism of Action: Direct action on intestinal mucosa
• Mechanism of Action: Requires bile for activity
• Mechanism of Action: Stimulates myenteric-plexus
• Mechanism of Action: Alters water-secretion

REFERENCES

• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 1006B, (ir)
• Baeyer, A., Annalen, 1880, 202, 69, (synth)
• Underwood, H.W. et al., J.A.C.S., 1930, 52, 4084
• Blicke, F.F. et al., J.A.C.S., 1932, 54, 332
• Hubacher, M.H. et al., J. Am. Pharm. Assoc., 1953, 42, 23
• Maute, R.L. et al., Anal. Chem., 1954, 26, 1723, (detn, CN(-))
• Davies, M. et al., J.C.S., 1954, 120, (ir)
• Ziegler, E. et al., Monatsh. Chem., 1969, 100, 1604, (pmr)
• Rousselet, R., J. Pharm. Belg., 1971, 26, 568, (ir, tlc)
• Bishop, E., Indicators, Pergamon, Oxford, 1972, 92; 192, (use)
• Holzbecher, Z. et al., Handbook of Organic Reagents in Inorganic Analysis, Horwood, Chichester, 1976, (use)
• Houben-Weyl, Methoden Org. Chem. (Houben-Weyl), 4th edn., (Wedemeyer, K.F., Ed.), 1976, 1093
• Shahine, S.A. et al., Microchem. J., 1976, 21, 286, (detn, Cl(-))
• Shahine, S.A. et al., Mikrochim. Acta, 1978, 2, 431, (detn, N2H4)
• Berger, S., Tetrahedron, 1981, 37, 1607, (cmr, tautom)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 5553, (synonyms)
• Al-Shammary, F.J. et al., Anal. Profiles Drug Subst., 1991, 20, 627, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 899
• Fitzgerald, L.J. et al., Acta Cryst. C, 1998, 54, 535-539, (cryst struct)
• Sigma-Aldrich Library of Stains, Dyes and Indicators, 563
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, PDO750