Squamolone

• Catalog No.: Bio-0328
• CAS Number: 40451-67-0
• M. F.: C5H8N2O2
• M. W.: 128.12922

SYNONYMS

• IUPAC name: 2-oxopyrrolidine-1-carboxamide
• IUPAC Traditional name: 2-oxopyrrolidine-1-carboxamide
• Synonyms: 1-Carbamoyl-2-pyrrolidone; 2-Oxo-1-pyrrolidinecarboxamide

DATABASE IDS

• CAS Number: 40451-67-0

PROPERTIES

• Application(s): Cytostatic
• Biological Source: Constit. of Annona squamosa and Hexalobus crispiflorus (Annonaceae). Also from Asimina triloba
• Mechanism of Action: Potent inhibition of mitochondrial NADH

REFERENCES

• Yang, T.H. et al., J. Chin. Chem. Soc. (Taipei), 1972, 19, 149; CA, 78, 16151w, (isol, uv, pmr, ms)
• Marquez, V.E. et al., J.O.C., 1980, 45, 5308, (struct, synth, ir, pmr, ms)
• Achenbach, H. et al., Annalen, 1982, 1623, (isol, cmr)
• Zhao, G.-X. et al., Phytochemistry, 1993, 33, 1065, (isol, synth)
• Sahai, M. et al., Indian J. Chem., Sect. B, 1996, 35, 510, (isol, synth, ir, pmr, cmr, ms)