Pidotimod

• Catalog No.: Bio-0324
• CAS Number: 121808-62-6
• M. F.: C9H12N2O4S
• M. W.: 244.26758

SYNONYMS

• IUPAC name: (4R)-3-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid
• IUPAC Traditional name: (4R)-3-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid
• Synonyms: Polimod; Onaka; Pigitil; Axil

DATABASE IDS

• CAS Number: 121808-62-6

PROPERTIES

• Application(s): Immunomodulator
• Application(s): Used for treatment of recurrent respiratory infections
• Description: Isomers
• Mechanism of Action: Activator of T-lymphocyctes and stimulator of granulocytes and macrophages

REFERENCES

• Eur. Pat., 1988, Poli Ind Chim, 276 752; CA, 109, 190876e, (synth, pharmacol)
• Coppi, G. et al., J. Chromatogr., 1991, 563, 385, (hplc)
• Migliorati, G. et al., Immunopharmacol. Immunotoxicol., 1992, 14, 737, (pharmacol)
• Pugliese, A. et al., Int. J. Immunother., 1992, 8, 212
• Dal Bo, L. et al., Boll. Chim. Farm., 1993, 132, 126, (hplc)
• Arzneim.-Forsch., 1994, 44, 1399, (numerous papers)
• Chiarenza, A. et al., Pharmacol. Toxicol., 1994, 74, 262, (pharmacol)
• Ayala, D.J. et al., Acta Cryst. C, 1995, 51, 473, (cryst struct)