Daphnoretin

• Catalog No.: Bio-0323
• CAS Number: 2034-69-7
• M. F.: C19H12O7
• M. W.: 352.29438

SYNONYMS

• IUPAC name: 7-hydroxy-6-methoxy-3-[(2-oxo-2H-chromen-7-yl)oxy]-2H-chromen-2-one
• IUPAC Traditional name: 7-hydroxy-6-methoxy-3-[(2-oxo-2H-chromen-7-yl)oxy]-2H-chromen-2-one
• Synonyms: Thymelol; Edgeworthin

DATABASE IDS

• CAS Number: 2034-69-7

PROPERTIES

• Application(s): Cytostatic
• Application(s): Anti-HIV-1 and Antifungal activity
• Biological Source: Constit. of Daphne mezereum and Wikstroemia viridiflora. A common bis-coumarin found in many plants
• Mechanism of Action: Protein kinase C activator

REFERENCES

• Tschesche, R. et al., Annalen, 1963, 662, 113, (struct)
• Tschesche, R. et al., Naturwissenschaften, 1963, 50, 521, (struct)
• Kirkiacharian, B. et al., Bull. Soc. Chim. Fr., 1966, 770, (synth)
• Reisch, J. et al., Planta Med., 1968, 16, 372, (deriv)
• Majumder, P.L. et al., Phytochemistry, 1974, 13, 1929, (Edgeworthin)
• Tandon, S. et al., Phytochemistry, 1977, 16, 1991, (isol)
• Cordell, G.A., J. Nat. Prod., 1984, 47, 84, (pmr, cmr)
• Ulubelen, A. et al., J. Nat. Prod., 1986, 49, 692, (Edgeworthin)
• Chakrabarti, R. et al., Phytochemistry, 1986, 25, 557, (isol)
• Ke, H. et al., Planta Med., 2000, 66, 564-567, (isol, activity)