Broxuridine

• Catalog No.: Bio-0319
• CAS Number: 59-14-3
• M. F.: C9H11BrN2O5
• M. W.: 307.09804

SYNONYMS

• IUPAC name: 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• Synonyms: Radibud; Bromouridine

DATABASE IDS

• CAS Number: 59-14-3

PROPERTIES

• Application(s): Antineoplastic
• Application(s): Virucide
• Mechanism of Action: Nucleoside antimetabolite
• Mechanism of Action: Incorporate into the DNA

REFERENCES

• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 375A, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 816C, (ir)
• Beltz, R.E. et al., J.A.C.S., 1955, 77, 736, (synth)
• Iball, J. et al., Nature (London), 1966, 209, 1230, (cryst struct)
• Hruska, F.E. et al., Can. J. Chem., 1974, 52, 497, (pmr)
• Davies, D.B., Stud. Biophys., 1976, 55, 29; CA, 85, 59065h, (cmr)
• Du Frain, R.J., Basic Life Sci., 1984, 29A, 41; 59; 83, (revs)
• Aoyama, H., Bull. Chem. Soc. Jpn., 1987, 60, 2073, (synth)
• Asakura, J. et al., J.O.C., 1990, 55, 4928, (synth, pmr, uv)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 460
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BNC750