Monocrotaline

• Catalog No.: Bio-0317
• CAS Number: 315-22-0
• M. F.: C16H23NO6
• M. W.: 325.35692

SYNONYMS

• IUPAC name: (1R,4R,5R,6R,16R)-5,6-dihydroxy-4,5,6-trimethyl-2,8-dioxa-13-azatricyclo[8.5.1.0^1^3,^1^6]hexadec-10-ene-3,7-dione
• IUPAC Traditional name: (1R,4R,5R,6R,16R)-5,6-dihydroxy-4,5,6-trimethyl-2,8-dioxa-13-azatricyclo[8.5.1.0^1^3,^1^6]hexadec-10-ene-3,7-dione

DATABASE IDS

• CAS Number: 315-22-0

PROPERTIES

• Application(s): Hepatotoxin
• Application(s): Antineoplastic activity esp. vs. adenocarcinoma
• Application(s): Male insect sterilant
• Biological Source: Alkaloid from Crotalaria retusa, Crotalaria spectabilis, Crotalaria aegyptiaca, Crotalaria burhia and Lindelofia spectabilis (Leguminosae, Boraginaceae)
• Mechanism of Action: Causes denudation of the hepatic sinusoidal endothelium and increased serum hyaluronic acid levels, along with superior transplanted cell engraftment

REFERENCES

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• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 1, 1080C, (nmr)
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