Arglabin

• Catalog No.: Bio-0309
• CAS Number: 84692-91-1
• M. F.: C15H18O3
• M. W.: 246.30162

SYNONYMS

• IUPAC name: (1S,3R,6S,10S,11R)-3,12-dimethyl-7-methylidene-2,9-dioxatetracyclo[9.3.0.0^1,^3.0^6,^1^0]tetradec-12-en-8-one
• IUPAC Traditional name: (1S,3R,6S,10S,11R)-3,12-dimethyl-7-methylidene-2,9-dioxatetracyclo[9.3.0.0^1,^3.0^6,^1^0]tetradec-12-en-8-one

DATABASE IDS

• CAS Number: 84692-91-1

PROPERTIES

• Application(s): Antineoplastic agent
• Biological Source: Constit. of Artemisia glabella, Artemisia myriantha and Artemisia mexicana
• Mechanism of Action: Farnesyl transferase inhibitor

REFERENCES

• Adekenov, S.M. et al., Khim. Prir. Soedin., 1982, 18, 655; Chem. Nat. Compd. (Engl. Transl.), 1982, 18, 623, (isol, ir, uv, ms, arglabin)
• Zdero, C. et al., Phytochemistry, 1990, 29, 189, (isol, pmr, arglabin)
• Appendino, G. et al., Fitoterapia, 1991, 62, 275, (struct)
• Adekenov, S.M. et al., Fitoterapia, 1995, 66, 142, (isol, pmr, cryst struct)
• Pat. Coop. Treaty (WIPO), 1998, 98 048 789; CA, 130, 480j, (arglabin, activity)
• Fazylova, A.S. et al., Khim. Prir. Soedin., 1999, 35, 305, (Arglabin)