Tetrahydroharmine

• Catalog No.: Bio-0305
• CAS Number: 17019-01-1
• M. F.: C13H16N2O
• M. W.: 216.27894

SYNONYMS

• IUPAC name: 7-methoxy-1-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
• IUPAC Traditional name: 7-methoxy-1-methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
• Synonyms: Leptaflorine; 1,2,3,4-Tetrahydro-7-methoxy-1-methyl-beta-carboline; 2,3,4,9-Tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole

DATABASE IDS

• CAS Number: 17019-01-1

PROPERTIES

• Biological Source: Alkaloid from Banisteriopsis caapi, Banisteriopsis argentea, Banisteriopsis inebrians, Leptactina densiflora, Peganum harmala and snuff used by South American Indians (Malphigiaceae, Rubiaceae, Zygophyllaceae).
• Application(s): Central nervous system stimulator
• Application(s): Hallucinogen
• Application(s): Antiparkinsolic
• Application(s): Anthelmintic
• Application(s): Coccidiostatic
• Mechanism of Action: MAO inhibitor
• Mechanism of Action: 5HT serotonin inhibitor

REFERENCES

• Perkin, W.H. et al., J.C.S., 1919, 115, 961, (synth)
• Paris, R.R. et al., Bull. Soc. Chim. Fr., 1957, 780, (isol, struct, uv, ir)
• Hochstein, F.A. et al., J.A.C.S., 1957, 79, 5735, (isol)
• Bernauer, K., Helv. Chim. Acta, 1964, 47, 1075, (isol)
• Koblicova, Z. et al., Chem. Ind. (London), 1966, 1342, (abs config)
• Ghosal, S., Planta Med., 1972, 21, 200, (cmr)
• Chrisey, L.A. et al., Heterocycles, 1990, 30, 267, (resoln)