Gastrodin

• Catalog No.: Bio-0293
• CAS Number: 62499-27-8
• M. F.: C13H18O7
• M. W.: 286.27782

SYNONYMS

• IUPAC name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
• IUPAC Traditional name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
• Synonyms: 4-beta- D Glucopyranosyloxybenzyl alcohol; 4-Hydroxybenzyl alcohol; 4-O-beta-D-Glucopyranoside; 4-(Hydroxymethyl)phenyl beta- D -glucopyranoside

DATABASE IDS

• CAS Number: 62499-27-8

PROPERTIES

• Application(s): Anticonvulsant
• Application(s): Antihypertensive
• Application(s): Hypnotic and Sedative props.
• Biological Source: Isol. from Gastrodia elata and Galeolae septentrionalis
• Mechanism of Action: Prevents glutamate- and NMDA-induced neurotoxicity
• Mechanism of Action: Increases extracellular glutamate level

REFERENCES

• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MED500
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 1, 1135B; 1135C; 1136A, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 352B; 352C; 353B, (nmr)
• Aldrich Library of FT-IR Spectra: Vapor Phase, 1989, 3, 1059C; 1059D, (ir)
• Spth, E., Monatsh. Chem., 1914, 35, 319, (synth)
• Carothers, W.H. et al., J.A.C.S., 1924, 46, 1675, (synth)
• Ofner, A., Helv. Chim. Acta, 1935, 18, 951, (synth)
• Watanabe, H. et al., CA, 1961, 55, 16697, (isol, deriv)
• Shannon, J.S., Aust. J. Chem., 1962, 15, 265, (ms)
• Hardegger, E. et al., Helv. Chim. Acta, 1963, 46, 1171, (isol)
• Mumford, F.E. et al., Phytochemistry, 1963, 2, 215, (isol)
• Torii, S. et al., J.O.C., 1979, 44, 3305, (synth)
• Taguchi, H. et al., Chem. Pharm. Bull., 1981, 29, 55, (Gastrodin)
• Inoue, S. et al., Yakugaku Zasshi, 1984, 104, 42, (Gastrodin)
• Nakatani, N. et al., Agric. Biol. Chem., 1987, 51, 2727, (synth, Gastrodin)
• Lewis, R.J., Food Additives Handbook, Van Nostrand Reinhold International, New York, 1989, MED500
• Encyclopedia of Food and Color Additives, (ed. Burdock, G.A.), CRC Press, 1997, 179-184, (derivs, occur, use)