Matrine

• Catalog No.: Bio-0290
• CAS Number: 519-02-8
• M. F.: C15H24N2O
• M. W.: 248.36386

SYNONYMS

• IUPAC name: (1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.0^2,^7.0^1^3,^1^7]heptadecan-6-one
• IUPAC Traditional name: (1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.0^2,^7.0^1^3,^1^7]heptadecan-6-one
• Synonyms: Lupanidine; Matridin-15-one

DATABASE IDS

• CAS Number: 519-02-8

PROPERTIES

• Application(s): Antiulcer
• Application(s): Antineoplastic
• Application(s): Antibacterial
• Biological Source: Alkaloid from roots of Sophora flavescens (Leguminosae)
• Mechanism of Action: Cholinergic
• Mechanism of Action: Sodium and calcium channel blocker

REFERENCES

• Bohlmann, F. et al., Chem. Ber., 1958, 91, 2176; 2189; 1975, 108, 1043, (ir, struct, config, cmr)
• Schtte, H.R. et al., Annalen, 1965, 685, 194, (biosynth)
• Mandell, L. et al., J.A.C.S., 1965, 87, 5234, (synth)
• Kojima, R. et al., Chem. Pharm. Bull., 1970, 18, 2555, (pharmacol)
• Vul'fson, N.S. et al., Khim. Geterotsikl. Soedin., 1974, 251; CA, 81, 13678z, (ms)
• Ueno, A. et al., Chem. Pharm. Bull., (footnote), 1975, 23, 2560, (abs config)
• Morinaga, K. et al., Chem. Pharm. Bull., 1978, 26, 2483, (pmr)
• Ibragimov, B.T. et al., Khim. Prir. Soedin., 1979, 15, 416; Chem. Nat. Compd. (Engl. Transl.), 1979, 15, 368, (cryst struct)
• Leeper, F.J. et al., Can. J. Chem., 1981, 59, 106, (biosynth)
• Ibragimov, B.T. et al., Khim. Prir. Soedin., 1982, 18, 71; Chem. Nat. Compd. (Engl. Transl.), 1982, 18, 66, (rev, stereochem)
• Abdusalamov, B.A., Khim. Prir. Soedin., 1984, 20, 3; Chem. Nat. Compd. (Engl. Transl.), 1984, 20, 1, (biosynth)
• Sakamoto, T. et al., Chem. Pharm. Bull., 1986, 34, 2018, (synth)
• Gonnella, N.C. et al., Magn. Reson. Chem., 1988, 26, 185, (pmr, cmr)