Skimmianine

• Catalog No.: Bio-0286
• CAS Number: 83-95-4
• M. F.: C14H13NO4
• M. W.: 259.25732

SYNONYMS

• IUPAC name: 4,7,8-trimethoxyfuro[2,3-b]quinoline
• IUPAC Traditional name: 4,7,8-trimethoxyfuro[2,3-b]quinoline
• Synonyms: Beta-Fagarine; Chloroxylonine; 7,8-Dimethoxydictamnine; Pentaphylline

DATABASE IDS

• CAS Number: 83-95-4

PROPERTIES

• Application(s): Spasmolytic agent
• Application(s): Antiviral
• Application(s): Diuretic
• Application(s): Protozoacide
• Biological Source: Alkaloid from Skimmia japonica and more than 40 other spp. from many genera, mostly in the family Rutaceae
• Mechanism of Action: Spasmolytic
• Mechanism of Action: Antagonist of 5-hydroxytryptamine receptors

REFERENCES

• Delofeu, V. et al., J.A.C.S., 1942, 64, 2326-2338, (isol, Skimmianine)
• Briggs, L.H. et al., J.C.S., 1960, 2458-2460, (ir, derivs)
• Robertson, A.V. et al., Aust. J. Chem., 1963, 16, 451, (pmr, Skimmianine, Evoxine)
• Clugston, D.M. et al., Can. J. Chem., 1965, 43, 2516-2521, (ms, Skimmianine)
• Grundon, M.F. et al., J.C.S. Perkin 1, 1974, 2181-2184; 1975, 302-304, (biosynth, Skimmianine, Evoxine)
• Tillequin, F. et al., J. Nat. Prod., 1982, 45, 486-488, (Skimmianine, haplopine, 7-Isopentyloxy--fagarine)
• Cox, O. et al., Acta Cryst. C, 1989, 45, 1263-1265, (crysts struct, Skimmianine)
• Jackson, G.E. et al., Spectrosc. Lett., 1990, 23, 971-982, (pmr, cmr, Skimmianine)
• Chakravarty, A.K. et al., Phytochemistry, 1999, 50, 1263-1266, (isol, pmr, cmr, ms, Skimmianine)