Fervenulin

• Catalog No.: Bio-0277
• CAS Number: 483-57-8
• M. F.: C7H7N5O2
• M. W.: 193.16278

SYNONYMS

• IUPAC name: 6,8-dimethyl-5H,6H,7H,8H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
• IUPAC Traditional name: 6,8-dimethyl-5H,6H,7H,8H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
• Synonyms: Antibiotic 10204-BII; Pulanomycin; Planomycin

DATABASE IDS

• CAS Number: 483-57-8

PROPERTIES

• Application(s): Antibiotic
• Biological Source: Isol. from Streptomyces fervens and Streptomyces rubrireticuli
• Mechanism of Action: Protein tyrosine phosphatase (PTP) inhibitor

REFERENCES

• Pfleiderer, W. et al., Annalen, 1958, 615, 42, (synth)
• Daves, G.D. et al., J.O.C., 1961, 26, 5256, (isol, struct, uv, ir)
• Yoneda, F. et al., J. Het. Chem., 1970, 7, 1443, (synth)
• Taylor, E.C. et al., J.O.C., 1975, 40, 2321, (synth, nmr)
• Senda, S. et al., J.A.C.S., 1977, 99, 7358, (synth)
• Ichiba, M. et al., J.O.C., 1978, 43, 469, (synth, ir, uv, ms, nmr)
• CRC Handb. of Antibiotic Compounds, (eds. Brdy, J. et al), CRC Press, Boca Raton, 1984, 5, 198, (props)
• Werner-Simon, S. et al., J. Het. Chem., 1996, 33, 949, (synth, derivs)
• Koshino, H. et al., Heterocycles, 2000, 52, 811-817, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, FBP300