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8-Oxoadenine

Catalog No. Bio-0272 Name InterBioScreen
CAS Number 21149-26-8 Website http://www.ibscreen.com
M. F. C5H5N5O Telephone +7 49652 40091
M. W. 151.1261 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 179751

SYNONYMS

IUPAC name
6-amino-8,9-dihydro-7H-purin-8-one
IUPAC Traditional name
6-amino-8,9-dihydro-7H-purin-8-one
Synonyms
6-Amino-1,7-dihydro-8 H -purin-8-one; 6-Amino-8-purinol
7,8-Dihydro-8- oxoadenine
8-Hydroxyadenine

DATABASE IDS

CAS Number 21149-26-8

PROPERTIES

Application(s) DNA mismatch in mutagenesis
Biological Source Found in the urine of humans suffering from leukaemia. Isol. from the ascidian Symplegma rubra
Mechanism of Action Induces misincorporation in in vitro DNA synthesis and mutation in NIH 3T3
Mechanism of Action Inhibits or blocks WRNp

DETAILS

REFERENCES

  • Robins, R.K., J.A.C.S., 1958, 80, 6671-6679, (synth, uv)
  • Brown, T. et al., Chem. Br., 1993, 29, 484-486, (rev)
  • Lindsay, B.S. et al., J. Nat. Prod., 1999, 62, 1573-1575, (isol)
  • Madyastha, K.M. et al., J.C.S. Perkin 1, 1999, 677-680, (isol)