Deacetoxymatricarin

• Catalog No.: Bio-0250
• CAS Number: 17946-87-1
• M. F.: C15H18O3
• M. W.: 246.30162

SYNONYMS

• IUPAC name: (3S,3aS,9aS,9bS)-3,6,9-trimethyl-2H,3H,3aH,4H,5H,7H,9aH,9bH-azuleno[4,5-b]furan-2,7-dione
• IUPAC Traditional name: (3S,3aS,9aS,9bS)-3,6,9-trimethyl-2H,3H,3aH,4H,5H,7H,9aH,9bH-azuleno[4,5-b]furan-2,7-dione
• Synonyms: Axillin; Leucomisin; Desacetoxymatricarin; Leukodin

DATABASE IDS

• CAS Number: 17946-87-1

PROPERTIES

• Application(s): Cytitoxic
• Application(s): Hepatotropic
• Biological Source: Constit. of Artemisia spp., Achillea spp., and Stevia pilosa
• Mechanism of Action: Effects NF-kB (Nuclear Factor-kB)

REFERENCES

• Rybalko, K.S., Zh. Obshch. Khim., 1963, 33, 2734; J. Gen. Chem. USSR (Engl. Transl.), 1963, 33, 2663, (Leucomisin)
• White, E.H.S. et al., Tetrahedron, 1969, 25, 2099, (synth)
• Marx, J.N. et al., Tetrahedron, 1969, 25, 2117, (isol)
• Shafizadeh, F. et al., J.O.C., 1972, 37, 3168, (isol)
• Bohlmann, F. et al., Tet. Lett., 1972, 621, (isol)
• Gonzlez, A.G. et al., An. Quim., Ser. C, 1976, 72C, 695, (isol)
• Martinez, V.M. et al., J. Nat. Prod., 1988, 51, 221, (pmr, cmr)
• Marco, J.A. et al., J. Nat. Prod., 1989, 52, 547, (cryst struct, pmr, cmr)
• Banerjee, A.K. et al., Tetrahedron, 1993, 49, 4761, (synth, rev)
• Ando, M. et al., J. Nat. Prod., 1994, 57, 433, (synth)
• Brengio, S.D. et al., J. Parasitol., 2000, 86, 407-412, (activity)