Griseofulvin

• Catalog No.: Bio-0245
• CAS Number: 126-07-8
• M. F.: C17H17ClO6
• M. W.: 352.76628

SYNONYMS

• IUPAC name: (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
• IUPAC Traditional name: (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
• Synonyms: Grifulvin; Idifulvin; Grisactin; Grisovin; Fulvicin; Curling factor; Gricin; Norofulvin; Likuden; Amudane; Fulcin

DATABASE IDS

• CAS Number: 126-07-8

PROPERTIES

• Application(s): Antifungal agent against
• Application(s): Trichophyton interdigitalis
• Application(s): Trichophyton mentagrophytes
• Application(s): Trichophyton megnini
• Application(s): activity against: Trichophyton rubrum
• Application(s): Trichophyton verrucosum
• Application(s): Trichophyton tonsurans
• Application(s): Trichophyton sulphureum
• Application(s): Trichophyton schoenleini
• Application(s): Trichophyton gallinae
• Application(s): Microsporum canis
• Application(s): Microsporum gypseum
• Application(s): Trichophyton crateriform
• Application(s): Epidermophyton floccosum.
• Application(s): Microsporum audouini
• Biological Source: Metab. of Penicillium griseofulvum
• Mechanism of Action: Binds tightly to new keratin which becomes highly resistant to fungal invasions

REFERENCES

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• Grove, J.F. et al., J.C.S., 1952, 3949; 3967, (struct, abs config)
• MacMillan, J., J.C.S., 1953, 1697, (deriv)
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