Guaiazulene

• Catalog No.: Bio-0241
• CAS Number: 489-84-9
• M. F.: C15H18
• M. W.: 198.30342

SYNONYMS

• IUPAC name: 1,4-dimethyl-7-(propan-2-yl)azulene
• IUPAC Traditional name: 1,4-dimethyl-7-(propan-2-yl)azulene
• Synonyms: Azulon; Azunol; Eucazulene; S - Guaiazulene; Kessazulene

DATABASE IDS

• CAS Number: 489-84-9

PROPERTIES

• Application(s): Antioxidant
• Application(s): Antiinflammatory agent
• Application(s): Also used to treat gastrointestinal disorders
• Application(s): Hepatoprotectant
• Biological Source: Found also in marine red algae and the gorgonian Euplexaura erecta
• Mechanism of Action: Antioxidant
• Mechanism of Action: Inhibits lipid peroxidation

REFERENCES

• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 40B, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 1, 955D, (ir)
• Aldrich Library of FT-IR Spectra: Vapor Phase, 1989, 3, 877B, (ir)
• Plattner, P.A. et al., Helv. Chim. Acta, 1949, 32, 2137; 2452, (synth)
• Sorm, F. et al., Coll. Czech. Chem. Comm., 1951, 16, 168; 626, (isol, synth)
• Caujolle, F. et al., Ann. Pharm. Fr., 1952, 10, 412, (pharmacol)
• Herz, A., Arzneim.-Forsch., 1953, 3, 253, (pharmacol)
• Jacob, T.M. et al., Tetrahedron, 1964, 20, 2821, (uv, synth)
• Llinas, J.R. et al., Can. J. Chem., 1975, 53, 2911, (pmr, cmr)
• Hoffmann, W. et al., Tet. Lett., 1975, 533, (synth)
• Mukherjee, D. et al., J.A.C.S., 1979, 101, 251, (synth)
• Fusetani, N. et al., Experientia, 1981, 37, 680, (isol)
• Li, M.K.W. et al., Tet. Lett., 1984, 25, 587, (derivs)
• Vidal-Ollivier, E. et al., J. Chromatogr., 1989, 463, 227, (hplc)
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 1688
• Kourounakis, A.P. et al., Arch. Pharm. (Weinheim, Ger.), 1997, 330, 7, (pharmacol)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DSJ800