Santonin

• Catalog No.: Bio-0231
• CAS Number: 481-06-1
• M. F.: C15H18O3
• M. W.: 246.30162

SYNONYMS

• IUPAC name: (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-2H,3H,3aH,4H,5H,5aH,8H,9bH-naphtho[1,2-b]furan-2,8-dione
• IUPAC Traditional name: (3S,3aS,5aS,9bS)-3,5a,9-trimethyl-2H,3H,3aH,4H,5H,5aH,8H,9bH-naphtho[1,2-b]furan-2,8-dione
• Synonyms: Alpha-Santonin

DATABASE IDS

• CAS Number: 481-06-1

PROPERTIES

• Application(s): Anthelmintic
• Biological Source: Occurs widely in plants, especially Artemisia spp.
• Mechanism of Action: Gabergic and cholinergic mechanisms

REFERENCES

• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 1, 709B, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 1, 1143C, (nmr)
• Pinhey, J.T. et al., Aust. J. Chem., 1965, 18, 543, (pmr)
• Asher, J.D.M. et al., J.C.S., 1965, 6041, (cryst struct)
• Boocock, D.G.B. et al., Chem. Comm., 1966, 90, (ms)
• Coggan, P. et al., J.C.S.(B), 1969, 237, (cryst struct)
• Karrer, W. et al., Konstitution und Vorkommen der Organischen Pflanzenstoffe, 2nd edn., Birkhuser Verlag, Basel, 1972, no. 1903, (occur)
• Heathcock, C.H., The Total Synthesis of Natural Products, (ApSimon, J.W., Ed.), Wiley, N.Y., 1973, 2, 315, (rev)
• Marshall, J.A. et al., J.O.C., 1978, 43, 1086, (synth)
• El-Feraly, F.S. et al., J.C.S. Perkin 1, 1983, 355, (synth)
• Kutney, J.P. et al., Can. J. Chem., 1984, 62, 2813, (synth)
• Van Hijfte, L. et al., Tetrahedron, 1984, 40, 4371, (synth)
• Shimizu, N. et al., Chem. Pharm. Bull., 1994, 42, 1160, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, SAU500