Allocryptopine

• Catalog No.: Bio-0227
• CAS Number: 485-91-6
• M. F.: C21H23NO5
• M. W.: 369.41102

SYNONYMS

• IUPAC name: 7,8-dimethoxy-11-methyl-17,19-dioxa-11-azatetracyclo[12.7.0.0^4,^9.0^1^6,^2^0]henicosa-1(21),4(9),5,7,14,16(20)-hexaen-2-one
• IUPAC Traditional name: 7,8-dimethoxy-11-methyl-17,19-dioxa-11-azatetracyclo[12.7.0.0^4,^9.0^1^6,^2^0]henicosa-1(21),4(9),5,7,14,16(20)-hexaen-2-one
• Synonyms: Alpha-Fagarine; Gamma-Homochelidonine; Beta-Homochelidonine

DATABASE IDS

• CAS Number: 485-91-6

PROPERTIES

• Application(s): Antihypertensive agent
• Application(s): Cardiac inhibitor
• Application(s): Respiratory stimulant
• Application(s): Muscle relaxant
• Application(s): Antiarrhythmic
• Biological Source: Alkaloid from a wide variety of genera in the Fumariaceae ( Corydalis, Dactylicapnos ), Papaveraceae ( Argemone, Bocconia, Eschscholtzia, Glaucium, Hunnemannia, Hylomecon, Macleaya, Meconopsis, Papaver, Sanguinaria,
• Mechanism of Action: Potassium outward current inducer

REFERENCES

• Ma, J.C.N. et al., Can. J. Chem., 1965, 43, 1849, (pmr)
• Hruban, L. et al., Coll. Czech. Chem. Comm., 1967, 32, 3414, (uv)
• Teitel, S. et al., Helv. Chim. Acta, 1973, 56, 553, (synth)
• Nakashima, T.T. et al., Org. Magn. Reson., 1973, 5, 9, (cmr)
• Battersby, A.R. et al., J.C.S. Perkin 1, 1975, 1147, (biosynth)
• Hanaoka, M. et al., Heterocycles, 1976, 4, 1685, (synth)
• Iwasa, K. et al., J.O.C., 1982, 47, 4275, (pmr, cmr)
• Sakai, T. et al., Acta Cryst. C, 1988, 44, 838, (cryst struct)
• Marek, J. et al., Coll. Czech. Chem. Comm., 1998, 63, 416-424, (cryst struct)
• Haworth, R.D. et al., J.C.S., 1926, 445, (synth)
• Deulofeu, V. et al., J.O.C., 1947, 12, 217, (struct)
• Redemann, C.E. et al., J.A.C.S., 1949, 71, 1030, (uv, struct)
• Dolejs, L. et al., Coll. Czech. Chem. Comm., 1964, 29, 2479, (ms)