3-Formylrifamycin

• Catalog No.: Bio-0222
• CAS Number: 13292-22-3
• M. F.: C38H47NO13
• M. W.: 725.77868

SYNONYMS

• IUPAC name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-formyl-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
• IUPAC Traditional name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-formyl-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
• Synonyms: Rifaldehyde

DATABASE IDS

• CAS Number: 13292-22-3

PROPERTIES

• Application(s): Antibiotic
• Biological Source: Metab. of Streptomyces mediterranei*
• Mechanism of Action: Inhibitor of bacterial DNA-dependent RNA polymerase and viral
• Mechanism of Action: RNA-dependent DNA polymerase

REFERENCES

• Maggi, N. et al., Antimicrob. Agents Chemother., 1965, 765-769, (metab, derivs)
• Netherlands Pat., 1966, Lepetit, 65 09 961; CA, 65, 5462c, (synth)
• Winsel, K. et al., Pharmazie, 1976, 31, 95-99, (metab)