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Inosine

Catalog No. Bio-0209 Name InterBioScreen
CAS Number 58-63-9 Website http://www.ibscreen.com
M. F. C10H12N4O5 Telephone +7 49652 40091
M. W. 268.22608 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 119255

SYNONYMS

IUPAC name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
IUPAC Traditional name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
Synonyms
Trophicardyl
Inosie
Oxiamine
Hypoxanthosine
Hypoxanthine riboside
Carnine

DATABASE IDS

CAS Number 58-63-9

PROPERTIES

Application(s) Cardiotonic
Application(s) Used to treat cardiac disorders
Biological Source Prod. by microorganisms, e.g. Bacillus subtilis, E. coli, Saccharomyces cerevisiae, Fusarium spp.
Mechanism of Action Activates cellular functions by base pairs with Adenine HFN72-P, Cytosine HDR44-O or Uracil BTP40-U

DETAILS

REFERENCES

  • Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 712B, (ir)
  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 215C, (nmr)
  • Gulland, J.M. et al., J.C.S., 1936, 765, (struct)
  • Hall, R.H., Biochem. Biophys. Res. Commun., 1963, 13, 394, (isol, deriv)
  • Kinichi, I. et al., Chem. Pharm. Bull., 1966, 14, 1377, (synth)
  • Japan. Pat., 1968, 68 13 215; CA, 70, 47808, (synth, isopropylidene)
  • Munns, A.R.I. et al., Acta Cryst. B, 1970, 26, 1114, (cryst struct)
  • Ger. Pat., 1972, 2038262; CA, 76, 99993e, (synth)
  • Chenon, M.T. et al., J.A.C.S., 1975, 97, 4627, (cmr)
  • Westhof, E. et al., Z. Naturforsch., C, 1975, 30, 131, (pmr)
  • Hawkes, G.E. et al., J.C.S. Perkin 2, 1977, 1268, (N-15 nmr)
  • Yamazaki, A. et al., J. Het. Chem., 1978, 15, 353, (rev, synth)
  • Aviado, D.M., J. Pharmacol., 1983, 14, 47, (rev, pharmacol)
  • Campoli-Richards, D.M. et al., Drugs, 1986, 32, 383, (rev, Inosine pranobex)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1551
  • De Simone, C. et al., Int. J. Immunopharmacol., 1991, 13, 19, (rev, Inosine pranobex)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 548; 1379
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, IDE000