Harmine

• Catalog No.: Bio-0207
• CAS Number: 442-51-3
• M. F.: C13H12N2O
• M. W.: 212.24718

SYNONYMS

• IUPAC name: 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
• IUPAC Traditional name: 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
• Synonyms: Banisterine; Telepathine; Yageine

DATABASE IDS

• CAS Number: 442-51-3

PROPERTIES

• Application(s): Antiparkinsonian agent
• Application(s): Active against gram-positive bacteria and fungi
• Biological Source: Alkaloid from Peganum harmala, several Banisteriopsis spp., Passiflora edulis and several other spp. (Zygophyllaceae, Malphigiaceae, Passifloraceae)
• Mechanism of Action: CNS stimulant
• Mechanism of Action: MAO-A inhibitor

REFERENCES

• Ahmad, A. et al., J. Ethnopharmacol., 1992, 35, 289-294, (activity)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1376
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, HAI500
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 682C, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 166B; 166C, (nmr)
• Spth, E. et al., Ber., 1930, 63, 120, (synth)
• Ismailov, N.A. et al., Farm. Farmakol, 1938, 4, 8, (use)
• Doig, G.G. et al., J.C.S., 1952, 3912, (uv)
• Schlittler, E. et al., Helv. Chim. Acta, 1953, 36, 996, (synth)
• Bishop, E., Indicators, Pergamon, Oxford, 1972, 695, (use)
• Hernandez, N.M.R. et al., Rev. Cubana Farm., 1977, 11, 249-255, (activity)
• Shoemaker, D.W. et al., J. Chromatogr., 1979, 174, 159, (glc, ms)
• Ross, S.A. et al., Fitoterapia, 1980, 6, 309-312, (activity)
• Al-Shamma, A. et al., J. Nat. Prod., 1981, 44, 745-747, (activity)
• Siddiqui, S. et al., Heterocycles, 1989, 29, 521, (isol, uv, ir, pmr, ms, bibl, Norharmine)