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Cycloserine

Catalog No. Bio-0191 Name InterBioScreen
CAS Number 68-41-7 Website http://www.ibscreen.com
M. F. C3H6N2O2 Telephone +7 49652 40091
M. W. 102.09194 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 2824

SYNONYMS

IUPAC name
(4R)-4-amino-1,2-oxazolidin-3-one
IUPAC Traditional name
(4R)-4-amino-1,2-oxazolidin-3-one
Synonyms
Antibiotic 106-7
Antibiotic Ro 1-9213
Closina
Oxamycin
Antibiotic I 1431
Seromycin
Farmiserina
Micoserina
Orientomycin
Cyclomycin
Oxymycin
Antibiotic E 733A
Antibiotic K 300
Antibiotic NJ 21
Antibiotic PA 94
Antibiotic 5915
Antibiotic 8217
Antibiotic 17452
Orientmycin

DATABASE IDS

CAS Number 68-41-7

PROPERTIES

Application(s) Shows antibiotic activity primarily against mycobacteria
Application(s) Tuberculostatic
Biological Source Prod. by Streptomyces garyphalus, Streptomyces orchidaceus, Streptomyces lavendulae and Streptomyces nagasakiensis
Mechanism of Action Inhibits cell-wall-synthesis in: Mycobacterium tuberculosis
Mechanism of Action Antagonizes the role of D-alanine in bacterial cell-wall-synthesis
Mechanism of Action Susceptible strains of gram-negative bacteria
Mechanism of Action Susceptible strains of gram-positive bacteria

DETAILS

REFERENCES

  • Aldrich Library of FT-IR Spectra, 1st edn., 1985, 1, 810A; 810D; 811A, (ir)
  • Aldrich Library of NMR Spectra, 2nd edn., 1983, 1, 678B; 678C; 678D, (nmr)
  • Harned, R.L. et al., Antibiot. Chemother. (Washington, D.C.), 1955, 5, 204, (struct)
  • Stammer, C.H. et al., J.A.C.S., 1955, 77, 2344; 2345; 2346; 1957, 79, 3236, (struct, synth, isol, resoln)
  • Neuhaus, F.C., Antibiotics (N.Y.), 1967, 1, 40, (rev)
  • Milne, G.W.A. et al., Tetrahedron, 1967, 23, 65, (nmr, ms)
  • Lamb, J.W., Anal. Profiles Drug Subst., 1972, 1, 53, (rev, synth, anal)
  • O'Brien, P., Met. Ions Biol. Syst., 1985, 19, 295, (rev, pharmacol)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 107, (synonyms)
  • El-Obeid, H.A. et al., Anal. Profiles Drug Subst., 1989, 18, 567, (rev)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 156
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CQH000