Aminopenicillanic acid

• Catalog No.: Bio-0187
• CAS Number: 551-16-6
• M. F.: C8H12N2O3S
• M. W.: 216.25748

SYNONYMS

• IUPAC name: (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• IUPAC Traditional name: (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

DATABASE IDS

• CAS Number: 551-16-6

PROPERTIES

• Application(s): Antibiotic against
• Application(s): Proteus mirabilis, Escherichia coli and Staphylococcus aureus
• Biological Source: Prod. by enzymic hydrol. of benzyl- or phenoxymethylpenicillins. Also prod. as metab. prod. of several penicillin-producing fungi, esp. when side-chain precursors are absent.
• Mechanism of Action: Lactamase inhibitor

REFERENCES

• Huber, F. et al., Cephalosporins Penicillins: Chem. Biol., (Flynn, E.H., Ed.), Academic Press, 1972, 27, (rev)
• Micetich, R.G. et al., Synthesis, 1976, 264, (oxide)
• Von Daehne, W. et al., J. Antibiot., 1980, 33, 451
• Moore, B.A. et al., Antimicrob. Agents Chemother., 1984, 20, 327, (props)
• Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 3, 129, (rev)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, PCU500
• Aldrich Library of NMR Spectra, 2nd edn., 1983, 1, 664A, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 1, 791C, (ir)
• Batchelor, R. et al., Nature (London), 1959, 183, 257, (manuf)