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Diphyllin

Catalog No. Bio-0182 Name InterBioScreen
CAS Number 22055-22-7 Website http://www.ibscreen.com
M. F. C21H16O7 Telephone +7 49652 40091
M. W. 380.34754 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 179728

SYNONYMS

IUPAC name
9-(2H-1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-1H,3H-naphtho[2,3-c]furan-1-one
IUPAC Traditional name
9-(2H-1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-1H,3H-naphtho[2,3-c]furan-1-one

DATABASE IDS

CAS Number 22055-22-7

PROPERTIES

Application(s) Cytotoxin
Application(s) Regulator of osteoclastic resorption lacunae and bone resorption
Biological Source Lignan from roots of Diphylleia grayi, leaves of Cleistanthus collinus, Justicia procumbens and Haplophyllum hispanicum
Mechanism of Action Potent V-ATPase inhibitor

DETAILS

REFERENCES

  • Horii, Z. et al., Chem. Comm., 1968, 653, (struct)
  • Govindachari, T.R. et al., Tetrahedron, 1969, 25, 2815, (isol, struct)
  • Okigawa, M. et al., Tetrahedron, 1970, 26, 4301, (isol)
  • Stevenson, R. et al., J.O.C., 1971, 36, 3450; 3453, (synth)
  • Arnold, B.J. et al., J.C.S. Perkin 1, 1973, 1266, (synth)
  • Horii, Z. et al., Chem. Pharm. Bull., 1977, 25, 1803, (synth)
  • Anjaneyulu, A.S.R. et al., Indian J. Chem., Sect. B, 1977, 15, 10, (isol, struct)
  • Momose, T. et al., Chem. Pharm. Bull., 1978, 26, 3195, (synth)
  • Gonzalez, A.G. et al., Planta Med., 1979, 36, 200-203, (Diphyllinins)
  • Fukamiya, N. et al., J. Nat. Prod., 1986, 49, 348
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CMV375