Nitrendipine

• Catalog No.: Bio-0179
• CAS Number: 39562-70-4
• M. F.: C18H20N2O6
• M. W.: 360.3612

SYNONYMS

• IUPAC name: 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC Traditional name: 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• Synonyms: Bayotensin; Baypress

DATABASE IDS

• CAS Number: 39562-70-4

PROPERTIES

• Application(s): Antihypertensive agent
• Application(s): Induces NO-release in endothelial cells
• Mechanism of Action: Potassium channel (IK Ca ) blocker
• Mechanism of Action: Calcium antagonist

REFERENCES

• Meyer, H. et al., Arzneim.-Forsch., 1981, 31, 407-409, (analogues, synth, pharmacol)
• Scriabine, A. et al., New Drugs Annu.: Cardiovasc. Drugs, 1984, 2, 37, (rev, pharmacol)
• Scriabine, A. et al., Nitrendipine 1984, (Eds.), Urban and Schwarzenberg, Baltimore, Md., 1984, (book)
• Kuhnert-Brandstaetter, M. et al., Sci. Pharm., 1986, 54, 71, (polymorphism)
• Hasegawa, G.R., Clin. Pharm., 1988, 7, 97, (rev)
• Soons, P.A. et al., Br. J. Clin. Pharmacol., 1991, 32, 11, (pharmacokinet, man)
• Soons, P.A. et al., Clin. Pharmacol. Ther. (St. Louis), 1991, 50, 394, (pharmacokinet, man)
• Mast, V. et al., Br. J. Clin. Pharmacol., 1992, 33, 51, (pharmacokinet, metab, enantiomers, man)
• Salameh, A. et al., Br. J. Pharmacol., 1996, 118, 1899, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 923
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, EMR600