Dipyridamole

• Catalog No.: Bio-0173
• CAS Number: 58-32-2
• M. F.: C24H40N8O4
• M. W.: 504.6256

SYNONYMS

• IUPAC name: 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol
• IUPAC Traditional name: 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol
• Synonyms: Curantyl; Persantin

DATABASE IDS

• CAS Number: 58-32-2

PROPERTIES

• Application(s): Coronary vasodilator
• Application(s): Enhances effects of anticoagulants
• Mechanism of Action: Vasodilator
• Mechanism of Action: Adenosine uptake inhibitor causing indirect adenosine receptor activation

REFERENCES

• Kadatz, R. et al., Arzneim.-Forsch., 1959, 9, 39, (pharmacol)
• U.K. Pat., 1959, 807 826; CA, 53, 12317, (synth, pharmacol)
• Beisenherz, G. et al., Arzneim.-Forsch., 1960, 10, 307, (metab)
• Takenaka, F. et al., Arzneim.-Forsch., 1972, 22, 892, (tox)
• Imai, K. et al., Yakugaku Zasshi, 1976, 96, 578; CA, 85, 108103, (synth)
• Adams, G.E., Adv. Med., 1980, 16, 171, (rev)
• Luger, P. et al., Acta Cryst. C, 1983, 39, 1454, (cryst struct)
• Rivey, M.D. et al., Drug Intell. Clin. Pharm., 1984, 18, 869, (rev, pharmacol)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 7225, (synonyms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 225
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, PCP250